The Headline
the week's biggest story
OpenAI ships GPT-5.4 with native computer-use and a 1M-token context window
OpenAI released GPT-5.4 this week in three tiers - standard, Thinking, and Pro - with a 1M-token context window available via API. the model scores 75% on OSWorld-Verified, surpassing the 72.4% human baseline, making it the first general-purpose frontier model to ship computer-use as a default API capability rather than a separate product.
for builders, this removes the last friction point between a prompt and an autonomous multi-step task. the 1M-token context fits full codebases, long document chains, and complex multi-document reasoning in a single call. the three-tier structure means most teams can find a price point that works today - whether for quick queries or heavy agentic workloads.
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The Build
tools, models, and dev releases
- Microsoft open-sources Phi-4-reasoning-vision-15B - the compact multimodal model scores 88.2% on ScreenSpot v2 GUI grounding and lets developers toggle reasoning on/off at inference time, trading latency for accuracy on computer-use tasks (More)
- Google ships Gemini 3.1 Flash Lite at $0.25/1M input tokens - the model outperforms Gemini 2.5 Flash on GPQA Diamond (86.9% vs 82.8%) while running 60% faster, making it a candidate default for high-volume production pipelines (More)
- VS Code 1.110 ships agent plugins, cross-session memory, and mid-response steering - developers can install prepackaged agent skill bundles, fork chat sessions mid-task to explore alternatives, and use `/compact` to manually control context window usage (More)
- Alibaba releases Qwen3.5 small series - the 9B model beats OpenAI's gpt-oss-120B on key benchmarks - the Apache 2.0 models use a hybrid Gated Delta Network + sparse MoE architecture; the 9B scores 81.7 on GPQA Diamond with 13x fewer parameters than the model it outperforms (More)
- OpenAI open-sources Symphony, an Elixir framework for autonomous coding-agent orchestration - the framework connects to Linear or any issue tracker, monitors the backlog, and spawns isolated implementation runs returning CI status, PR review feedback, and walkthrough videos as proof of work (More)
Founder Fuel
funding, acquisitions, and market moves
- Anduril targets $60B valuation in $4B round led by Thrive Capital and a16z - the raise nearly doubles the defense-AI startup's $30.5B valuation from 2025 in under a year, putting it in the same capital tier as frontier model labs (More)
- Oracle plans thousands of layoffs as AI data-center debt tops $100B - cuts span multiple divisions as Oracle burns through cash building infrastructure for OpenAI and xAI; earnings drop March 10 and are expected to test investor patience with the AI infrastructure bet (More)
- Netflix acquires Ben Affleck's AI filmmaking startup InterPositive - the 16-person team built per-production AI models for post-production tasks - color grading, VFX, reframing - trained from existing footage rather than generating video from prompts (More)
- Amazon cuts 100+ robotics engineers and cancels its multi-arm warehouse robot project - the company cited AI efficiency gains as the driver, a signal that its automation roadmap has shifted from physical hardware toward software-led approaches (More)
Big Picture
science, research, and ideas beyond AI
- a natural flavonoid shown to selectively clear senescent cells and slow age-related decline in mice - the compound dihydromyricetin uses a dual mechanism, protecting healthy cells while killing senescent ones via mitochondrial apoptosis, and cleared Alzheimer's plaques in mouse models while improving cognition (More)
- ARPA-H awards $22M for a 200-person trial of a repurposed HIV drug targeting the "jumping genes" that drive aging inflammation - the study, led by Rochester, Brown, and UConn, tests TPN-101 in adults aged 60-65 and will track mobility, cognition, and molecular aging markers (More)
- IBM and university researchers synthesize the first half-Möbius molecule, verified with quantum computing - the ring-shaped carbon molecule features a new electronic topology class and can be reversibly switched between chirality states, opening a path to engineered molecular electronics (More)
- Cambridge researchers find electrons traverse solar materials in 18 femtoseconds via a "molecular catapult" mechanism - rapid charge separation occurred with minimal energy offset, overturning established solar design theory and pointing to new cell architectures that sidestep the traditional speed-versus-efficiency tradeoff (More)
The World
regulation, policy, and geopolitics
- US Commerce Department drafts rules requiring a permit for every Nvidia and AMD AI chip exported anywhere in the world - the 129-page draft would require licenses even for shipments under 1,000 GPUs and may mandate large-volume buyers invest in US AI infrastructure as a condition of approval (More)
- China's 15th five-year plan (2026-2030) bets the entire economy on AI, with an "AI+" action plan spanning manufacturing, logistics, healthcare, and education - the 141-page blueprint released at the National People's Congress on March 5 mentions AI more than 50 times and sets state-owned enterprises as anchor adopters to force AI into industry (More)
- Trump's March 11 deadline triggers a federal move to override state AI laws, with $42B in broadband funding as leverage - the Commerce Department's target list includes Colorado's algorithmic discrimination ban and California's frontier AI safety rules; 23 bipartisan AGs have filed opposition as unconstitutional overreach (More)
Go Deeper
long reads, podcasts, and documentaries
- why your next flight is likelier to hit turbulence - The New Yorker | Burkhard Bilger. climate change is quietly doubling clear-air turbulence - the invisible phenomenon behind some of the most violent in-flight accidents of the past two years - and the skies have no fix in sight. (Read)
- this startup claims it can stop lightning and prevent catastrophic wildfires - MIT Technology Review | James Temple. Skyward Wildfire wants to seed the atmosphere with metallic chaff to prevent lightning strikes before they ignite the next megafire - and asks whether we should let any company control the weather. (Read)
- greatest guitarists of all time, history & future of music - Lex Fridman Podcast | Lex Fridman and Rick Beato. a 3.5-hour conversation from Django Reinhardt to Metallica that turns into one of the more honest discussions about what AI is doing to creative craft. (Listen)
- ask me anything - mindscape, march 2026 - Sean Carroll's Mindscape Podcast | Sean Carroll. Carroll previews a paper distinguishing four fundamentally different meanings of "information" - from Shannon's bits to thermodynamics to Wheeler's "it from bit" - and why the distinction matters for how we understand reality. (Listen)
The Colony
events and community
- tomorrow: Monthly Hangout for advanced AI builders - Sunday, March 8 at Espresso House Mittelweg 130, Hamburg - no agenda, just Cursor and Claude Code builders from 9:30 AM (RSVP)
- next Build Fridays: Friday, March 13 at betahaus, Eifflerstr. 43, Hamburg - bring your laptop and work on your startup from 4 PM, intros at 7 PM (RSVP)
a single beaver can fell up to 200 trees per year using only its teeth. this week, GPT-5.4 shipped with native computer-use and a 1M-token context window. the next dam brief may write itself.
stay curious,
Alex & Vlady
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